Àú³Î ȨÆäÀÌÁö
³í¹®Åõ°í±ÔÁ¤
  ÇÐȸÁö > ´ëÇÑÀÓ»óÅëÁõÇÐȸÁö °Ë»ö
19(01) 8-15
https://doi.org/10.35827/cp.2020.19.1.8
°ñ¼ö ÈíÀÎ-Ç÷¼ÒÆÇ Ç³ºÎ Ç÷Àå°ú È÷¾Ë·ç·Ð»êÀÇ °üÀý°­³» ÁÖ»çÀÇ È¿°ú ºñ±³
À̺´Âù1¤ý±è¾Æ¶õ1¤ý±èÀº°æ2¤ý±è¼±Á¤3¤ý±è»óÁØ4
¼º±Õ°ü´ëÇб³ ÀÇ°ú´ëÇÐ »ï¼º¼­¿ïº´¿ø ÀçÈ°ÀÇÇб³½Ç1, °¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ³»°úÇб³½Ç ³»ºÐºñ³»°ú2, ÀÌ¿£¼¿ ¹ÙÀÌ¿À, R&D ¼¾ÅÍ3, ¼­¿ïÁØÀçÈ°ÀÇÇаú4
Clinical Pain 2020 Jun; 19(01) 8-15
Effects of Bone Marrow Aspirate Concentrate-Platelet-rich Plasma Versus Hyaluronic Acid on Patients with Knee Osteoarthritis: A Randomized Controlled Trial
Byung Chan Lee, M.D.1, Ah Ran Kim, M.D.1, Eun Kyung Kim, M.S.2, Sun Jeong Kim, M.S.3 and Sang Jun Kim, M.D., Ph.D.4
1Department of Physical and Rehabilitation Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 2Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, 3R&D Center, ENCell Co. Ltd, 4Seoul Jun Rehabilitation Clinic, Seoul, Korea
Objective: To compare the therapeutic efficacy of the bone marrow aspirate concentrate (BMAC)- platelet-rich plasma (PRP) complex with hyaluronic acid in patients with knee osteoarthritis. Method: Thirty-four patients with knee osteoarthritis participated in this study. Seventeen patients in the study group underwent BMAC and PRP extraction followed by intra-articular injection of BMAC-PRP complex within affected knee. Seventeen patients in the control group underwent intra-articular injection of hyaluronic acid. Knee injury, osteoarthritic outcome score (KOOS), and EuroQol-5D (EQ-5D) questionnaire were evaluated before, one month, three months, and six months after the injection. Results: There were statistically significant temporal differences in total KOOS scores in both BMAC-PRP and HA groups. However, there were no significant group difference in the study period. In the Sports and Recreational Function Scale, there was statistically significant improvement in the BMAC-PRP group compared to the HA group at three months (p=0.041). There were no side effects or complications in both groups. Conclusion: Intra-articular injection of BMAC-PRP showed better functional recovery in the OA at three months and this can be an alternative treatment in terms of functional recovery in the OA in addition to the decrease of pain.
Clinical Pain 2020 Jun; 19(01) 8-15
Keyword : Bone marrow aspiration concentrates, Platelet rich plasma, Hyaluronic acid, Osteoarthritis, Knee


[02447] ¼­¿ï µ¿´ë¹®±¸ °æÈñ´ë·Î 23 (ȸ±âµ¿) (°æÈñ´ëÇб³º´¿ø ÀçÈ°ÀÇÇаú ³»)
TEL : (¹®Àǽð£: 9½Ã-17½Ã) 02-958-8567 FAX : 02-958-8557 E-mail : kapainmed@hanmail.net
Copyright by The Korean Association of Pain Medicine. All rights reserved